Replication fork stability confers chemoresistance in BRCA-deficient cells

• Profiling BRCA1-BRCT interactions and their functional relevance at amino acid resolution

  2025 Nucleic Acids Research article Biochemistry, Genetics and Molecular Biology BRCA gene mutations in cancer Open access

  3

  citations
• Mechanism of BRCA1–BARD1 function in DNA end resection and DNA protection

  2024 Nature article Biochemistry, Genetics and Molecular Biology DNA Repair Mechanisms Open access

  67

  citations
• (Single-stranded DNA) gaps in understanding BRCAness

  2024 Trends in Genetics review Biochemistry, Genetics and Molecular Biology DNA Repair Mechanisms Open access

  24

  citations
• EXO1 protects BRCA1-deficient cells against toxic DNA lesions

  2024 Molecular Cell article Biochemistry, Genetics and Molecular Biology DNA Repair Mechanisms Open access cited by 2 patents

  44

  citations
• EXO1-mediated DNA repair by single-strand annealing is essential for BRCA1-deficient cells

  2023 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology DNA Repair Mechanisms Open access

  4

  citations
• Sister chromatid exchanges induced by perturbed replication can form independently of BRCA1, BRCA2 and RAD51

  2022 Nature Communications article Biochemistry, Genetics and Molecular Biology DNA Repair Mechanisms Open access

  47

  citations
• PARP Inhibition and Beyond in BRCA-Associated Breast Cancer in Women: A State-Of-The-Art Summary of Preclinical Research on Risk Reduction and Clinical Benefits

  2022 Medical Principles and Practice article Medicine PARP inhibition in cancer therapy Open access

  11

  citations
• Functional Characterization of PALB2 Variants of Uncertain Significance: Toward Cancer Risk and Therapy Response Prediction

  2020 Frontiers in Molecular Biosciences article Biochemistry, Genetics and Molecular Biology BRCA gene mutations in cancer Open access

  16

  citations

8 results