Identification and Functional Characterization of Distinct Critically Important Bone Morphogenetic Protein-specific Response Elements in the Id1 Promoter

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  2025 Cardiovascular Research article Medicine Pulmonary Hypertension Research and Treatments Open access

  10

  citations
• TGM6 is a helminth secretory product that mimics TGF-β binding to TGFBR2 to antagonize signaling in fibroblasts

  2025 Nature Communications article Biochemistry, Genetics and Molecular Biology TGF-β signaling in diseases Open access

  9

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• TGF-β receptor-specific NanoBRET Target Engagement in living cells for high-throughput kinase inhibitor screens

  2024 SLAS DISCOVERY article Biochemistry, Genetics and Molecular Biology TGF-β signaling in diseases Open access

  3

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• Osmolarity‐Induced Altered Intracellular Molecular Crowding Drives Osteoarthritis Pathology

  2024 Advanced Science article Medicine Osteoarthritis Treatment and Mechanisms Open access

  16

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• TGM6, a helminth secretory product, mimics TGF-β binding to TβRII to antagonize TGF-β signaling in fibroblasts

  2023 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology TGF-β signaling in diseases Open access

  5

  citations
• Data from Autocrine Bone Morphogenetic Protein-9 Signals through Activin Receptor-like Kinase-2/Smad1/Smad4 to Promote Ovarian Cancer Cell Proliferation

  2023 other Biochemistry, Genetics and Molecular Biology TGF-β signaling in diseases Open access

  0

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• Physosmotic Induction of Chondrogenic Maturation Is TGF-β Dependent and Enhanced by Calcineurin Inhibitor FK506

  2022 International Journal of Molecular Sciences article Medicine Osteoarthritis Treatment and Mechanisms Open access

  8

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• Crystal structures of BMPRII extracellular domain in binary and ternary receptor complexes with BMP10

  2022 Nature Communications article Biochemistry, Genetics and Molecular Biology TGF-β signaling in diseases Open access

  23

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• Establishment of Embryonic Zebrafish Xenograft Assays to Investigate TGF-β Family Signaling in Human Breast Cancer Progression

  2022 Methods in molecular biology book-chapter Biochemistry, Genetics and Molecular Biology Zebrafish Biomedical Research Applications Open access

  5

  citations
• Inhibition of the prolyl isomerase Pin1 improves endothelial function and attenuates vascular remodelling in pulmonary hypertension by inhibiting TGF-β signalling

  2021 Angiogenesis article Medicine Pulmonary Hypertension Research and Treatments Open access

  18

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• Inhibiting Endothelial Cell Function in Normal and Tumor Angiogenesis Using BMP Type I Receptor Macrocyclic Kinase Inhibitors

  2021 Cancers article Biochemistry, Genetics and Molecular Biology Angiogenesis and VEGF in Cancer Open access

  10

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• TGF-β-Induced Endothelial to Mesenchymal Transition Is Determined by a Balance Between SNAIL and ID Factors

  2021 Frontiers in Cell and Developmental Biology article Biochemistry, Genetics and Molecular Biology TGF-β signaling in diseases Open access

  49

  citations
• TRAF4 inhibits bladder cancer progression by promoting BMP/SMAD signalling pathway

  2020 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology TGF-β signaling in diseases Open access

  1

  citations
• Cell Signaling Pathway Reporters in Adult Hematopoietic Stem Cells

  2020 Cells article Medicine Hematopoietic Stem Cell Transplantation Open access

  19

  citations
• Cercosporamide inhibits bone morphogenetic protein receptor type I kinase activity in zebrafish

  2020 Disease Models & Mechanisms article Biochemistry, Genetics and Molecular Biology TGF-β signaling in diseases Open access

  9

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• Bone morphogenetic protein receptors: Structure, function and targeting by selective small molecule kinase inhibitors

  2020 Bone article Biochemistry, Genetics and Molecular Biology TGF-β signaling in diseases Open access cited by 13 patents

  118

  citations
• Cercosporamide inhibits bone morphogenetic protein receptor type I kinase activity in zebrafish

  2020 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology TGF-β signaling in diseases Open access

  0

  citations
• A Signaling Crosstalk between BMP9 and HGF/c-Met Regulates Mouse Adult Liver Progenitor Cell Survival

  2020 Cells article Medicine Liver physiology and pathology Open access

  14

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• Mutant ACVR1 Arrests Glial Cell Differentiation to Drive Tumorigenesis in Pediatric Gliomas

  2020 Cancer Cell article Medicine Glioma Diagnosis and Treatment Open access

  102

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19 results