Chronic Inflammation (Inflammaging) and Its Potential Contribution to Age-Associated Diseases

• Immune aging biomarkers for clinical trials

  2026 Nature Medicine article Biochemistry, Genetics and Molecular Biology Genetics, Aging, and Longevity in Model Organisms

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  citations
• High-dimensional single-cell phenotyping unveils persistent differences in immune cell profiles between severe and moderate seasonal influenza

  2025 Frontiers in Immunology article Medicine Influenza Virus Research Studies Open access

  4

  citations
• A chronic low dose of Δ9-tetrahydrocannabinol (3 mg / kg / 21 d) reorganizes the disturbed wound healing process and accelerates wound closure in old female mice

  2025 Experimental Gerontology article Medicine Wound Healing and Treatments Open access

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  citations
• Ethnicity-specific patterns of epigenetic age acceleration in rheumatoid arthritis

  2025 GeroScience article Biochemistry, Genetics and Molecular Biology Epigenetics and DNA Methylation Open access

  1

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• Delayed cutaneous wound healing in young and old female mice is associated with differential growth factor release but not inflammatory cytokine secretion

  2025 Biogerontology article Medicine Wound Healing and Treatments Open access

  5

  citations
• The effect of BCG vaccination in the elderly on infectious and non-infectious immune-mediated diseases

  2024 Journal of Infection article Immunology and Microbiology Immune responses and vaccinations Open access

  6

  citations
• Computational identification of natural senotherapeutic compounds that mimic dasatinib based on gene expression data

  2024 Scientific Reports article Medicine Telomeres, Telomerase, and Senescence Open access

  18

  citations
• Age‐related subtypes of late life depression and mortality: A prospective clinical cohort study

  2024 International Journal of Geriatric Psychiatry article Medicine Frailty in Older Adults Open access

  6

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• Distinct baseline immune characteristics associated with responses to conjugated and unconjugated pneumococcal polysaccharide vaccines in older adults

  2024 Nature Immunology article Medicine Pneumonia and Respiratory Infections Open access

  47

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• Changes in the physical behaviour of older adults during the 13 weeks GOTO intervention explain a boost in immuno-metabolic health

  2023 medRxiv preprint Medicine Physical Activity and Health Open access

  4

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• Cellular and Transcriptional Signature of the Nasal Mucosa is Associated with Susceptibility to Pneumococcal Carriage in Older Adults

  2023 medRxiv preprint Medicine Pneumonia and Respiratory Infections Open access

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• Distinct baseline immune characteristics associated with responses to conjugated and unconjugated pneumococcal polysaccharide vaccines in older adults

  2023 medRxiv preprint Medicine Pneumonia and Respiratory Infections Open access

  4

  citations
• Transcriptional activation of Jun and Fos members of the AP‐1 complex is a conserved signature of immune aging that contributes to inflammaging

  2023 Aging Cell article Biochemistry, Genetics and Molecular Biology Genetics, Aging, and Longevity in Model Organisms Open access

  98

  citations
• Association of Torquetenovirus Viremia with Physical Frailty and Cognitive Impairment in Three Independent European Cohorts

  2022 Gerontology article Medicine Frailty in Older Adults Open access

  16

  citations
• Transcriptional activation of Jun and Fos members of the AP-1 complex is a conserved signature of immune aging that contributes to inflammaging

  2022 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Genetics, Aging, and Longevity in Model Organisms Open access

  6

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• Insights Into the Effects of Mucosal Epithelial and Innate Immune Dysfunction in Older People on Host Interactions With Streptococcus pneumoniae

  2021 Frontiers in Cellular and Infection Microbiology article Medicine Pneumonia and Respiratory Infections Open access

  9

  citations
• Inhibition of Cdc42 activity extends lifespan and decreases circulating inflammatory cytokines in aged female C57BL/6 mice

  2020 Aging Cell article Biochemistry, Genetics and Molecular Biology Genetics, Aging, and Longevity in Model Organisms Open access cited by 1 patent

  71

  citations

17 results