February 21, 2011 article Open access MEK-ERK pathway modulation ameliorates disease phenotypes in a mouse model of Noonan syndrome associated with the Raf1L613V mutation Journal of Clinical Investigation DOI: 10.1172/jci44929 Full text (OA) OpenAlex Authors 0 Author list not loaded yet. Cited by 4 stored of 243 Search Sort Most cited Newest Oldest Patent citations Title Any typearticle review book-chapter conference-paper preprint dissertation book dataset other Any fieldAgricultural and Biological Sciences Arts and Humanities Biochemistry, Genetics and Molecular Biology Business, Management and Accounting Chemical Engineering Chemistry Computer Science Decision Sciences Dentistry Earth and Planetary Sciences Economics, Econometrics and Finance Energy Engineering Environmental Science Health Professions Immunology and Microbiology Materials Science Mathematics Medicine Neuroscience Nursing Pharmacology, Toxicology and Pharmaceutics Physics and Astronomy Psychology Social Sciences Veterinary Open access SHP2 binds directly to SOS1 to enable RAS activation 2026 bioRxiv (Cold Spring Harbor Laboratory) preprint Biochemistry, Genetics and Molecular Biology Protein Tyrosine Phosphatases Open access 0 citations Targeting Interleukin-8–Mediated Cellular Crosstalk Reverses Hypertrophic Cardiomyopathy and Cardiac Fibrosis in Noonan Syndrome 2026 Circulation article Medicine Cardiac Fibrosis and Remodeling Open access 2 citations The seventh international RASopathies symposium: Pathways to a cure—expanding knowledge, enhancing research, and therapeutic discovery 2022 American Journal of Medical Genetics Part A article Biochemistry, Genetics and Molecular Biology Protein Tyrosine Phosphatases Open access 15 citations Interference with ERK-dimerization at the nucleocytosolic interface targets pathological ERK1/2 signaling without cardiotoxic side-effects 2020 Nature Communications article Biochemistry, Genetics and Molecular Biology Melanoma and MAPK Pathways Open access 63 citations 4 results References 0