A second endogenous cannabinoid that modulates long-term potentiation

• Translational Application of the Five-Star Matrix for the Structure-Guided Optimization of a Bicyclopiperazine DEL Hit into Bcpz 1.5: A Potent Monoacylglycerol Lipase Inhibitor with Functional Inhibition in Human Brain Homogenate and Efficacy in Neuroinflammatory Models

  2026 Journal of Medicinal Chemistry article Computer Science Computational Drug Discovery Methods

  0

  citations
• Stimulus-Driven Remodeling of Microglial Endocannabinoid Metabolism Illuminates ABHD12 Function in Immunity

  2026 ACS Chemical Neuroscience article Medicine Cannabis and Cannabinoid Research

  0

  citations
• Highly Specific Miniaturized Fluorescent Monoacylglycerol Lipase Probes Enable Translational Research

  2025 Journal of the American Chemical Society article Medicine Cannabis and Cannabinoid Research Open access

  12

  citations
• Structure-Guided Discovery of cis-Hexahydro-pyrido-oxazinones as Reversible, Drug-like Monoacylglycerol Lipase Inhibitors

  2024 Journal of Medicinal Chemistry article Medicine Cannabis and Cannabinoid Research Open access

  9

  citations
• Enhancing Drug Discovery and Development through the Integration of Medicinal Chemistry, Chemical Biology, and Academia-Industry Partnerships: Insights from Roche’s Endocannabinoid System Projects

  2024 CHIMIA International Journal for Chemistry article Medicine Cannabis and Cannabinoid Research Open access

  4

  citations
• P2X 7 receptor‐dependent increase in endocannabinoid 2‐arachidonoyl glycerol production by neuronal cells in culture: Dynamics and mechanism

  2024 British Journal of Pharmacology article Medicine Cannabis and Cannabinoid Research Open access

  5

  citations
• ABHD6 selectively controls metabotropic-dependent increases in 2-AG production

  2022 bioRxiv (Cold Spring Harbor Laboratory) preprint Medicine Cannabis and Cannabinoid Research Open access

  4

  citations

7 results