POLYMER-BASED DRUG DELIVERY SYSTEM
Espacenet
Family 89029551
Abstract
The present invention relates to a polymer-based drug delivery system as such and its use in a method of treatment of a range of diseases and disorders, including cancer. The drug delivery system of the present invention is suitable for intracranial delivery and release of cytotoxic agents, in particular radioisotope-functionalized agents such as deoxyuridine.
Inventors 6
- Jensen, Andreas Tue Ingemann
- Straathof, Natan
- Tang, Qing
- Thisgaard, Helge
- Matthias Barz Aachen author as filed: Barz, Matthias
- Gabriela Giannina Schäfer Aachen author as filed: Schäfer, Gabriela
Inventors are linked to an Aachen author when surname and first name match exactly one author.
Applicants
- DANMARKS TEKNISKE UNIVERSITET
- UNIVERSITY OF SOUTHERN DENMARK
- REGION SYDDANMARK
- UNIVERSITEIT LEIDEN GBS Leiden
- Univ Danmarks Tekniske
- Univ Of Southern Denmark
Cited papers 0 in the database
Non-patent literature as cited (3)
- - E. J. L. STEEN ET AL., ACS NANO, vol. 14, no. 1255942-06-3, 2020, pages 568 - 584
- - KORTYLEWICZ ZBIGNIEW P. ET AL: "Norepinephrine-Transporter-Targeted and DNA-Co-Targeted Theranostic Guanidines", vol. 63, no. 5, 24 June 2019 (2019-06-24), US, pages 2051 - 2073, XP055774850, ISSN: 0022-2623, Retrieved from the Internet <URL:https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.9b00437> DOI: 10.1021/acs.jmedchem.9b00437
- - XIAO-HONG YANG: "[beta]-Cyclodextrin Complexes of Hydrolyzable Adamantanoyl-IUdR Prodrugs - Radioiodination and Biodistribution in Mice Bearing Implanted KBALB Tumours", CURRENT RADIOPHARMACEUTICALS, vol. 2, no. 2, 1 April 2009 (2009-04-01), NL, pages 137 - 142, XP093163177, ISSN: 1874-4710, DOI: 10.2174/1874471010902020137