MULTIPLEXING TARGETING AND IMAGING AGENTS
Espacenet
Family 85158698
Abstract
Provided herein are compounds of formula | and formula ll that are useful in the targeting and/or imaging of biological specimens, in particular as agents that may be used for targeting and 5 imaging the hepatobiliary system and related cells. The compounds represent multiplexing tracers comprising a fluorescent dye-based targeting moiety and a secondary moiety that may include a second imaging label and/or a therapeutic agent. R1 R2 R4 R3 R7 R10 R5 R8 Re R6 / N [ÎICB L I R11 R12 (I) R1 R2 R4 Ra R7 R8 RQ R10 R5 Re / N @ |/ | N X n R14 R14 (ll) 10
Inventors 5
- Fijs, van Leeuwen
- Danny, van Willigen
- Meta, Roestenberg
- Clarize, de Korne
- Tessa, Buckle
Inventors are linked to an Aachen author when surname and first name match exactly one author.
Applicants
- ACADEMISCH ZIEKENHUIS LEIDEN (H.O.D.N. LUMC) GBS Leiden
Cited papers 2 in the database
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