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MASS-SPECTROMETRIC METHOD FOR PATHOGEN DETECTION

Espacenet Family 74666419

Abstract

The invention relates to a mass-spectrometry method for detecting pathogens. The method is highly sensitive and is therefore particularly useful for detecting peptides that are present in only low concentrations, such as pathogen peptides in a swab sample obtained from a subject.

Inventors 3

  1. Thomas Hankemeier Aachen author as filed: Hankemeier, Thomas
  2. Amy C. Harms Aachen author as filed: Harms, Amy C
  3. Nicolas Drouin Aachen author as filed: Drouin, Nicolas FP

Inventors are linked to an Aachen author when surname and first name match exactly one author.

Applicants

Cited papers 3 in the database

Non-patent literature as cited (9)
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  • - DHAENENS, THE ANALYTICAL SCIENTIST, 15 September 2020 (2020-09-15)
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  • - LILY TING ET AL: "MS3 eliminates ratio distortion in isobaric multiplexed quantitative proteomics", NATURE METHODS, vol. 8, no. 11, 2 October 2011 (2011-10-02), New York, pages 937 - 940, XP055521887, ISSN: 1548-7091, DOI: 10.1038/nmeth.1714
  • - MACEK BORIS ET AL: "Top-down Protein Sequencing and MS 3 on a Hybrid Linear Quadrupole Ion Trap-Orbitrap Mass Spectrometer", 4 January 2006 (2006-01-04), pages 500042 - 200, XP055922109, Retrieved from the Internet <URL:https://www.sciencedirect.com/science/article/pii/S1535947620303418> [retrieved on 20220517]
  • - SPECHT HARRISON ET AL: "Optimizing Accuracy and Depth of Protein Quantification in Experiments Using Isobaric Carriers", JOURNAL OF PROTEOME RESEARCH, vol. 20, no. 1, 14 November 2020 (2020-11-14), pages 880 - 887, XP055922103, ISSN: 1535-3893, Retrieved from the Internet <URL:https://pubs.acs.org/doi/pdf/10.1021/acs.jproteome.0c00675> DOI: 10.1021/acs.jproteome.0c00675