MEANS AND METHODS FOR TREATING BACTERIAL INFECTIONS

Abstract

[0001] The present invention relates to a pharmaceutical composition comprising or consisting of a combination of (a) two or more peptides, each peptide consisting of or comprising 17 to 23 amino acids, wherein the amino acids in positions 1 to 23, counted from the N-terminus, are as follows (1) G, S or lacking; (2) C or lacking; (3) K or R; (4) K or R; (5) Y, W or F; (6) K or R; (7) K or R; (8) F, W or L; (9) K or R; (10) K or L or lacking; (11) W, L or F; (12) K or R; (13) F, Y or C; (14) K or R; (15) G or Q; (16) K or R; (17) F, L or W; (18) F or W; (19) F, L or W; (20) W or F; (21) C or lacking; (22) F or G or lacking; (23) G or lacking; or (b) one or more peptides, each peptide consisting of or comprising 17 to 23 amino acids, wherein the amino acids in positions 1 to 23, counted from the N-terminus, are as follows (1) G, S or lacking; (2) C or lacking; (3) K or R; (4) K or R; (5) Y, W or F; (6) K or R; (7) K or R; (8) F, W or L; (9) K or R; (10) K or L or lacking; (11) W, L or F; (12) K or R; (13) F, Y or C; (14) K or R; (15) G or Q; (16) K or R; (17) F, L or W; (18) F or W; (19) F, L or W; (20) W or F; (21) C or lacking; (22) F or G or lacking; (23) G or lacking, and one or more antibiotics selected from small organic molecule antibiotics such as ceftriaxone, oxacillin, amoxicillin, amikacin, ciprofloxacin, erythromycin, imipenem and tetracycline, and peptidic antibiotics such as daptomycin and vancomycin.

Inventors 15

1. Brandenburg, Klaus
2. Heinbockel, Lena
3. Reiling, Norbert
4. Martinez de Tejada, Guillermo
5. Schurholz, Tobias
6. Mauss, Karl
7. Weindl, Gunther
8. Martinez, de Tejada Guillermo
9. Klaus, Brandenburg
10. Lena, Heinbockel
11. Norbert, Reiling
12. Guillermo, Martinez de Tejada
13. Tobias, Schuerholz
14. Karl, Mauss
15. Guenther, Weindl

Inventors are linked to an Aachen author when surname and first name match exactly one author.

Applicants

• FORSCHUNGSZENTRUM BORSTEL LEIBNIZ-ZENTRUM FUR MEDIZIN UND BIOWSSENSCHAFTEN
• FREIE UNIVERSITAT BERLIN
• UNIVERSITAT ZU LUBECK
• RHEINISCH-WESTFALISCHE TECHNISCHE HOCHSCHULE (RWTH) AACHEN RWTH Aachen University
• Univ Berlin Freie
• Univ zu Lubeck
• FORSCHUNGSZENTRUM BORSTEL LEIBNIZ-ZENTRUM FUR MEDIZIN UND BIOWISSENSCHAFTEN
• フォルシュングスツェントルム ボルシュテル ライプニッツツェントルム フュール メディツィン ウント ビオヴィッセンシャフテン
• Forschungszentrum Borstel Leibniz Zentrum Fuer Medizin Und Biowissenschaften
• Univ Luebeck

Cited papers 0 in the database

Cited patents 6