METHOD AND DEVICE FOR SOLVENT EVAPORATION FROM A LIQUID FEED
Abstract
The present invention relates to a device and an arrangement for selective solvent evaporation from a liquid feed, the feed comprising one or more components diluted in at least a first solvent or a solvent blend, comprising:a) a first tubular vessel having a distal end or a channel suitable for the formation of a droplet of a first volume, at an inflow rate r<sub>1</sub>, at the tip or in the lumen of the tubular vessel, andb) means for subjecting the droplet to a solvent removal step at an evaporation rate r<sub>2</sub> to evaporate at least part of the first solvent or solvent blend, to accumulate the components in the feed in the droplet during the evaporation process at an accumulation rate r<sub>3</sub>, to obtain a concentrated feed volume in a concentrated droplet, wherein the evaporation and/or inflow rates are continuously adjusted to achieve a desired accumulation rate. The invention further relates to a method for selective solvent removal from an analyte mixture obtained in a chromatographic separation process.
Inventors 4
- Thomas Hankemeier Aachen author as filed: Hankemeier, Thomas
- Schoonen, Jan-Willem
- van der Linden, Heiko Jan
- Paul Vulto Aachen author as filed: Vulto, Paul
Inventors are linked to an Aachen author when surname and first name match exactly one author.
Applicants
- Universiteit Leiden GBS Leiden
Cited papers 0 in the database
Non-patent literature as cited (2)
- - TIAN, H. ET AL., J CHROMATOGR A, vol. 1137, no. 1, 2006, pages 42 - 8
- - TIAN, H.J. XUY. GUAN, J SEP SCI, vol. 31, no. 10, 2008, pages 1677 - 85